Fibromyalgia

Fibromyalgia is a complex disorder, and the exact etiology is unknown. More recent research has uncovered many possible theories we will cover below, though the sequence of events that causes fibromyalgia remains unknown. Research shows biochemical, metabolic, and immunoregulatory abnormalities associated with fibromyalgia.

The biochemical changes seen in the Central Nervous System (CNS), the low levels of serotonin (feel good neurotransmitter), the 4-fold increase in nerve growth factor, and the elevated levels of substance P, all lead to a whole-body hypersensitivity to pain and suggest that fibromyalgia may be a condition of abnormal central processing of pain input or central sensitization.

Researchers also have found low levels of adenosine triphosphate, ATP (energy) in red blood cells of patients with fibromyalgia. Although the significance is unknown, some suggest that low platelet serotonin levels can be explained if platelet ATP levels are also low. ATP is necessary to move and then hold serotonin in platelets. More investigation into ATP and the link to serotonin is needed.

Growth hormone

Growth hormone, produced during delta (deep) sleep, is involved in tissue repair. Therefore, disrupted stage 4 (delta) sleep associated with fibromyalgia may account for low levels of growth hormone. Growth hormone stimulates the production of insulinlike growth factor I (IGF-I) in the liver. This can result in fatigue, weakness, loss of strength, and pain

Nerve growth factor

In some studies, nerve growth factor was 4 times higher in the spinal fluid of patients with fibromyalgia than in others. This is important nerve growth factor enhances the production of substance P (pain messenger) nerves, increasing the person's sensitivity or awareness to pain. Nerve growth factor also may play a role in spreading or redistributing perceived pain signals.

Toxicity

A newer theory regarding the etiology of fibromyalgia discovered by Dr. San Amand is cellular toxicity. A genetic defect may cause retention of phosphates inside cell membranes that interefere with ATP production (energy). Accumulation of phosphates is followed by accumulation of calcium. This results in severe fatigue and pain.

It is possible that there may be more than one cause of fibromyalgia and many of these theories could contribute, as different treatments often work for different people. (i.e. Dr. San Amand’s Gui protocol produces amazing results in some, and not in others.)

Acupuncture

Acupuncture offers relief for many fibromyalgia patients, although this is generally a longer, and more involved treatment protocol. Acupuncture, combined with nutrition, biofeedback, and herbal medicine can address many of the above potential causes of fibromyalgia. Herbal and amino acid therapy can increase serotonin naturally and promote restful sleep, acupuncture dramatically decreases stress and anxiety, while resetting the central nervous system and blocking the body’s increased sensitivity to pain (research shows acupuncture decreases substance P), and biofeedback can reduce stress in the nerves. Often other health issues occur simultaneously with fibromyalgia, and addressing those issues will increase effectiveness of the treatment.

Groundbreaking research at Mayo Clinic showed acupuncture as an important treatment for fibromyalgia. The study found “Fatigue, anxiety and pain were the most significantly improved symptoms during the follow-up period”.